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Biomedical & Translational Research

My research explores the intersection of medicine, technology, and community health, including gene expression analysis in spaceflight, surgical decision-making, and health system design.

Due to institutional guidelines and academic integrity protections related to pre-publication research, full manuscripts will be publicly released in May 2026.

Below are selected projects across translational research, surgical outcomes, and global health equity.

Surgical Systems & Clinical Outcomes

Case Study Analysis – Trauma Surgery

Mixed-methods investigation on intraoperative decision-making and surgical precision in high-acuity trauma cases.

  • Collaborated with trauma and acute-care surgeons from Baylor College of Medicine, University of Melbourne, and Emory University.

  • Studied hemorrhage control, anatomic reconstruction, and operative decision-making in complex trauma settings.

  • Performed quantitative analysis (SPSS, Python) of operative duration, blood loss, and stabilization intervals to identify performance correlations.

  • Conducted qualitative coding (NVivo) of surgeon interviews to evaluate incision methods, vascular repair, and hemostatic timing.

  • Findings defined evidence-based parameters for trauma surgery precision and adaptability under high-stress conditions.

  • Supported development of surgical frameworks to reduce complications and improve long-term recovery outcomes.

Tools: SPSS · Python (pandas, matplotlib) · NVivo · Excel

Clinical Urology Case Study — Diagnostic and Management Insights

Qualitative and computational analysis of clinical reasoning and treatment pathways in urologic care.

  • Collaborated with a Memorial Hermann–affiliated urologic surgeon in Houston, TX.

  • Investigated diagnostic workflows for BPH, prostate cancer, kidney stones, erectile dysfunction, UTIs, and hematuria.

  • Analyzed clinical interviews and chart reviews using NVivo to identify diagnostic trends and therapeutic frameworks.

  • Designed simulated patient cases based on age, symptoms, and comorbidities to model real-world diagnostic reasoning.

  • Developed a computational diagnostic model in Python (NumPy, scikit-learn) to map symptom clusters and management outcomes.

  • Aimed to improve precision in early diagnosis and create a foundation for AI-assisted clinical decision support.

Tools: NVivo · Python (NumPy, scikit-learn) · Excel

Independent Study — Intraoperative Complications in Abdominal Surgery

Mixed-methods international study examining complication patterns and optimization strategies in minimally invasive abdominal surgery.

  • Collaborated with global surgical faculty from Stanford Medicine, NHS systems, Newcastle University, Royal College of Surgeons of Edinburgh, and University of Porto.

  • Analyzed intraoperative complications in laparoscopic and minimally invasive abdominal procedures.

  • Conducted quantitative review of operative data (SPSS, Python) focusing on conversion rates, bleeding, and morbidity trends.

  • Performed qualitative coding (NVivo) of surgeon interviews on decision-making during adhesiolysis, vascular control, and anastomotic repair.

  • Identified how trocar geometry, visualization fidelity, and instrument precision influence complication rates and operative outcomes.

  • Proposed a technique-based optimization framework integrating data analytics with global surgical best practices.

Tools: SPSS · Python (pandas, seaborn) · NVivo

Oral & Maxillofacial Surgery Research – Tumor Prevention and Environmental Health

Collaborative study on early detection and surgical prevention of oral and maxillofacial tumors in low-resource settings.

  • Partnered with oral and maxillofacial surgeons and public health experts across Houston and Pakistan.

  • Investigated how environmental carcinogens, tobacco, and betel nut use contribute to oral tumor incidence and delayed diagnosis.

  • Analyzed clinical registry data (SPSS, Python) to correlate incidence with environmental and socioeconomic factors.

  • Conducted qualitative interviews (NVivo) with clinicians and patients to identify diagnostic and screening barriers.

  • Developed a surgical prevention framework focused on community screening, oncologic education, and early pathology integration.

  • Demonstrated that early excision of precancerous lesions can significantly reduce morbidity and tumor progression.

Tools: SPSS · Python (NumPy, seaborn) · NVivo · Excel

AP Research – Surgeons’ Perspectives on Robotic vs. Laparoscopic Surgery in Oncology

Global qualitative study comparing surgical innovation, outcomes, and accessibility in oncologic care.

  • Surveyed and interviewed oncologic surgeons across multiple continents to compare robotic and laparoscopic techniques.

  • Explored how technology impacts surgical precision, decision-making, and postoperative outcomes across healthcare systems.

  • Analyzed data in Excel, assessing learning curves, infrastructure costs, and clinical variability between methods.

  • Conducted thematic coding of surgeon insights on tactile feedback, ergonomics, and tumor resection accuracy.

  • Evaluated global disparities in access and training for robotic systems, emphasizing sustainable innovation in surgery.

  • Concluded that robotic surgery improves dexterity and visualization but requires careful cost-benefit and equity considerations.

Tools: Excel — Global Qualitative & Cost-Outcome Comparative Analysis

Research Aid — INOV8 Orthopedics, Houston, TX

Clinical and translational research experience supporting infection control and procedural innovation in orthopedic surgery.

  • Assisted attending surgeons and investigators in ongoing studies on surgical site infections (SSI) in total joint arthroplasty.

  • Conducted literature reviews, collected clinical data, and contributed to structured research discussions and documentation.

  • Experienced cadaveric training sessions, gaining understanding in orthopedic anatomy, robotic-assisted techniques, and procedural accuracy.

  • Supported logistical and technical tasks in research operations, enhancing lab efficiency and data organization.

  • Strengthened understanding of infection control, perioperative care, and engineering integration in orthopedic surgery.

Skills & Focus Areas: Clinical Data Analysis · SSI Prevention · Orthopedic Surgery · Cadaveric Anatomy · Surgical Robotics

Neuroscience & Oncology

Collaborative Meta-Analysis – Traumatic Brain Injury and Glioma Risk (Ongoing)

Global meta-analysis exploring neuroinflammatory and oncogenic links between brain injury and tumor development.

  • Conducted under the mentorship of a Texas A&M University professor, analyzing global clinical datasets on TBI and glioma incidence.

  • Investigated immune modulation, neuroinflammatory cascades, and tumor microenvironment remodeling as mechanistic pathways.

  • Used R Studio and SPSS to calculate pooled effect sizes, assess heterogeneity, and control for confounding variables.

  • Identified how chronic inflammation and glial dysregulation may increase long-term susceptibility to gliomagenesis.

  • Connected findings to neurosurgical trauma care and neuro-oncology prevention, highlighting implications for clinical follow-up and research.

Tools: R Studio · SPSS · Excel — Meta-Analysis & Neuro-Oncology Research

Oral & Maxillofacial Surgery Research – Tumor Prevention and Environmental Health

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Collaborative study on early detection and prevention of oral tumors in low-resource settings.

  • Led an international research collaboration with oral and maxillofacial surgeons and public health experts in Houston and Pakistan.

  • Investigated how environmental carcinogens, tobacco, and betel nut use contribute to oral and maxillofacial tumor incidence.

  • Analyzed regional clinical registries using SPSS and Python (NumPy, seaborn) to identify incidence trends and socioeconomic correlations.

  • Conducted qualitative interviews and case reviews in NVivo to identify barriers to early diagnosis and surgical intervention.

  • Developed a surgical prevention framework emphasizing community screening, oncologic education, and diagnostic access.

  • Demonstrated that early detection and timely excision of precancerous lesions significantly reduce tumor burden and morbidity.

Tools: SPSS · Python (NumPy, seaborn) · NVivo · Excel — Epidemiologic & Surgical Oncology Research

Defense Health Study – Physiological and Occupational Risk Factors in U.S. Navy Personnel (Ongoing)

Independent analysis of long-term health outcomes in maritime and deployment environments.

  • Conducted an independent study on occupational health risks among U.S. Navy service members, focusing on physiological stress and environmental exposure.

  • Reviewed clinical and epidemiologic data from Department of Defense health reports and scientific literature.

  • Analyzed hearing loss, spinal injuries, and chronic fatigue syndromes linked to maritime operations.

  • Used Python (pandas, seaborn) and SPSS for trend modeling and data visualization across service duration and role type.

  • Identified strong correlations between high-decibel exposure, vibration-induced microtrauma, and musculoskeletal strain.

  • Proposed enhanced preventive ergonomics and monitoring systems to improve long-term health outcomes for active-duty personnel.

Tools: Python (pandas, seaborn) · SPSS · Excel — Occupational & Environmental Health Analysis

Public Health & Global Health Equity

Both of these projects center on public and global health equity, a theme I strive to integrate into all my research, whether in clinical, translational, or community-based work.

 

Empower & Connect Global Study — Education’s Role in Healthcare and Social Infrastructure

International mixed-methods study on how education and engineering drive healthcare equity.

  • Co-led an international research project in Kitale, Kenya, partnering with local government, healthcare teams, and educational institutions.

  • Investigated how education, engineering, and infrastructure initiatives can enhance healthcare delivery and community resilience in underserved regions.

  • Conducted field interviews and surveys across surrounding villages to assess socioeconomic barriers, cultural factors, and system inefficiencies in health access.

  • Found that integrating technical education, public awareness, and infrastructure support improved both community health literacy and sustainable service delivery.

  • Served as a lead coordinator during Empower & Connect’s early phase, contributing to direct research implementation and data synthesis.

Tools & Methods: Qualitative Analysis · Survey Design · Stakeholder Interviews · Socio-Technical Systems Evaluation

Empower & Connect Biological Study — Water Quality and Community Health

Mixed-methods research in Kenya and India on sanitation, contamination, and health equity.

  • Co-led an international study in Kitale, Kenya, and the urban slums of Dharavi and Parel, Mumbai, in collaboration with local public health teams and Grant Government Medical College.

  • Investigated how environmental water contamination affects disease prevalence, sanitation practices, and community resilience in underserved populations.

  • Collected and analyzed biological water samples via local laboratories, testing for microbial load, chemical contaminants, and pH balance.

  • Conducted 100+ resident interviews to capture behavioral, cultural, and infrastructural perspectives on sanitation and disease prevention.

  • Integrated quantitative and qualitative findings to identify links between infrastructure deficits, public health inequities, and preventable disease transmission.

Tools & Methods: Mixed-Methods Design · Microbial Assay Interpretation · Structured Interviews · Thematic Analysis · Community-Based Participatory Research

Biomedical & Space Medicine

Biomedical Research — NASA Ames Research Center

 

Collaborative research on molecular adaptation and human health in spaceflight.

  • Collaborated with NASA’s GeneLab research team to analyze transcriptomic datasets from the Rodent Research-6 mission, examining how microgravity alters hepatic gene expression and stress-response regulation.

  • Investigated key molecular pathways involved in mitochondrial function, oxidative stress, and metabolic adaptation under microgravity conditions.

  • Explored how these findings translate to biomedical applications on Earth, particularly in understanding organ resilience and environmental stress tolerance.

  • Contributed to the development of hypotheses connecting gene regulation in spaceflight to systemic health outcomes in terrestrial environments.

Tools & Methods: RNA-Seq Workflow · FastQC · STAR Alignment · DESeq2 · STRING · Cytoscape · DAVID · WebGestalt · PCA & Volcano Plot Visualization

Biomedical Research — NASA Ames Research Center (Ongoing)

Collaborative research with mentors from NASA Ames Research Center and Boeing-affiliated professionals.

  • Ongoing project integrating data from multiple Rodent Research missions to examine how microgravity affects liver metabolism, gene regulation, and systemic stress responses.

  • Conducts cross-mission comparisons of transcriptomic datasets to identify shared molecular signatures of adaptation, focusing on pathways related to oxidative stress, mitochondrial dynamics, and metabolic regulation.

  • Aims to translate insights from spaceflight biology into applications for astronaut health and Earth-based medicine, particularly in chronic disease prevention and metabolic resilience.

Tools & Methods: Comparative Transcriptomics · Pathway Enrichment (STRING, Cytoscape, DAVID, WebGestalt) · PCA & Volcano Plot Visualization

© 2026 Yuvraj Parmar. All rights reserved.

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